East Asian ancestry¶
Definition
AI-generated
Coarse label for probabilistic genetic ties to a broad world region in biobanks and reference panels; distinct from social identity alone.
Topics
Why it matters in GWAS¶
Population structure, demographic history, and mating patterns affect allele frequencies, LD, relatedness, and cross-cohort portability—central to GWAS design and interpretation.
Example usage¶
"The replication cohort stratified analyses by East Asian ancestry to evaluate effect-size portability across populations."
Related terms¶
References¶
- Hartl DL, Clark AG. (2007). Principles of Population Genetics. Sinauer Associates.
- Jobling MA, Hurles ME, Tyler-Smith C. (2013). Human Evolutionary Genetics. Garland Science.
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