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Anticodon

Definition
AI-generated

An anticodon is a triplet of nucleotides in a transfer RNA (tRNA) molecule that base-pairs with a complementary mRNA codon during translation, helping deliver the correct amino acid to the ribosome.

Why it matters in GWAS

Most disease-associated common variants are noncoding, but coding changes can alter translation kinetics or tRNA usage; anticodon-related biology appears in specialized functional studies rather than typical GWAS summaries.

Example usage

"The suppressor tRNA carried a mutant anticodon predicted to read through the premature termination codon."

References

  • Alberts B, et al. (2015). Molecular Biology of the Cell. 6th ed. Garland Science.

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