Unsupervised Learning¶
Definition
AI-generated
Unsupervised learning discovers structure in inputs without per-example labels—via clustering, low-dimensional embeddings, density modeling, or self-supervised pretext tasks—often as a precursor to downstream prediction or interpretation.
Topics
Why it matters in GWAS¶
Unsupervised steps include PCA for population structure, UMAP or autoencoders on single-cell data, and latent models for batch correction. Latent factors may align with ancestry or hidden relatedness, which can confound later association analyses if not regressed or modeled explicitly.
Example usage¶
"A replication analysis checks whether assumptions tied to Unsupervised Learning remain stable across cohorts."
Related terms¶
References¶
- Bishop CM. (2006). Pattern Recognition and Machine Learning. Springer.
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