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Untranslated region (UTR)

Definition
AI-generated

5′ or 3′ mRNA segments regulating stability, localization, and initiation beyond the coding ORF.

Why it matters in GWAS

GWAS hits are interpreted through gene structure, regulation, and variant consequence; molecular vocabulary connects association statistics to mechanism.

Example usage

"Downstream interpretation uses Untranslated region (UTR) to connect statistical evidence with biological context."

References

  • Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.

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