Skip to content

Uniparental disomy (UPD)

Definition
AI-generated

Both copies of a chromosome inherited from the same parent—reveals imprinting disorders or recessive risk.

Topics
Core genetics
Related
Genomic Imprinting Homozygosity Mendelian Disease

Why it matters in GWAS

GWAS hits are interpreted through gene structure, regulation, and variant consequence; molecular vocabulary connects association statistics to mechanism.

Example usage

"Downstream interpretation uses Uniparental disomy (UPD) to connect statistical evidence with biological context."

Genomic Imprinting Homozygosity Mendelian Disease
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.
← Underfitting Unique Molecular Identifier (UMI) →

Last updated (UTC · Git history)