Skip to content

Transition/transversion ratio (Ti/Tv)

Definition
AI-generated

The transition/transversion ratio (Ti/Tv) compares counts of transition SNVs (A↔G, C↔T) to transversions.

Topics
Sequencing Data Analysis
Related
Single Nucleotide Variant (SNV) Variant Calling

Why it matters in GWAS

Deviations from expected Ti/Tv can indicate systematic errors, contamination, or bad filtering—useful global QC before association.

Example usage

"Ti/Tv was 2.1 genome-wide, consistent with high-quality SNV calls."

Single Nucleotide Variant (SNV) Variant Calling
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Wang K, et al. (2010). ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res.
← Transformer Translation →

Last updated (UTC · Git history)