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Single-cell ATAC-seq (scATAC-seq)

Definition
AI-generated

ATAC-seq performed on single cells or single nuclei resolving accessibility heterogeneity and lineage-specific regulatory programs.

Why it matters in GWAS

Bioinformatics methods determine how variants, expression, and epigenetic state are measured and summarized—shaping GWAS covariates, multi-omic integration, and functional follow-up.

Example usage

"Quality-controlled Single-cell ATAC-seq (scATAC-seq) data were used to prioritize robust loci and downstream functional follow-up."

References

  • Lesk AM. (2019). Introduction to Bioinformatics. Oxford University Press.

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