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Sex-linked

Definition
AI-generated

Association with sex chromosomes—often X-linked inheritance patterns with sex differences in prevalence or GWAS modeling.

Topics

Why it matters in GWAS

These concepts shape how we expect variants to act (penetrance, heterogeneity, threshold models) and how GWAS signals should be interpreted alongside family-based evidence.

Example usage

"The methods section includes Sex-linked to support interpretation of the primary findings."

References

  • Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.

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