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Microsatellite

Definition
AI-generated

A microsatellite is a short tandem repeat, typically with repeat units of 1 to 6 base pairs.

Topics
Core genetics
Related
Repeat Expansion Short Tandem Repeat (STR) Tandem Repeat

Why it matters in GWAS

Microsatellites are highly polymorphic and can be functionally important, but they are often missing from standard SNP-centric association analyses.

Example usage

"Sequencing follow-up suggested a microsatellite length polymorphism near the lead SNP."

Repeat Expansion Short Tandem Repeat (STR) Tandem Repeat
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Gymrek M. (2017). A genomic view of short tandem repeats. Curr Opin Genet Dev.
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