Skip to content

Metagenomics

Definition
AI-generated

Metagenomics is the sequencing and analysis of DNA from mixed microbial communities without culturing individual species, yielding taxonomic profiles, gene content, and strain-level variation from samples such as stool or oral swabs.

Topics
Sequencing and omics tech
Related
Bioinformatics Genomics Microbiome

Why it matters in GWAS

Shotgun metagenomics links host SNPs to microbial gene abundance and pathway activity; it complements 16S surveys and feeds microbiome–host multi-omics studies.

Example usage

"Shotgun metagenomics quantified species copy number for association with host polygenic scores."

Bioinformatics Genomics Microbiome Multi-Omics
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Quince C, et al. (2017). Shotgun metagenomics, from sampling to analysis. Nat Biotechnol.
← Metagenome Metaphase →

Last updated (UTC · Git history)