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Kaplan–Meier Method

Definition
AI-generated

A nonparametric estimator of the survival function—the probability of remaining event-free up to time *t*—from censored time-to-event data, usually displayed as a step function with confidence intervals.

Topics
Regression and multivariate statistics Visualization
Synonyms
Kaplan–Meier estimator Product-limit estimator
Related
Censoring Hazard Ratio (HR) Polygenic Risk Score (PRS)

Why it matters in GWAS

Post-GWAS translation and stratified reporting sometimes show Kaplan–Meier curves by genotype or polygenic score quartile to illustrate how genetic burden shifts the survival curve, complementing hazard ratios from regression. Visual checks also clarify informative censoring or subgroup-specific follow-up.

Example usage

"Kaplan–Meier Method appears in the methods to support interpretation of the primary results."

Censoring Hazard Ratio (HR) Polygenic Risk Score (PRS) Survival Analysis Time-to-Event
Related-term network

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Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Kaplan EL, Meier P. (1958). Nonparametric estimation from incomplete observations. J Am Stat Assoc.
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