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Homo heidelbergensis

Definition
AI-generated

Middle Pleistocene hominin group hypothesized to connect Neanderthal and modern human ancestry.

Why it matters in GWAS

Population structure, demographic history, and mating patterns affect allele frequencies, LD, relatedness, and cross-cohort portability—central to GWAS design and interpretation.

Example usage

"Genotype QC and interpretation explicitly accounted for Homo heidelbergensis status at candidate loci."

References

  • Hartl DL, Clark AG. (2007). Principles of Population Genetics. Sinauer Associates.
  • Jobling MA, Hurles ME, Tyler-Smith C. (2013). Human Evolutionary Genetics. Garland Science.

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