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GWAS Diversity Monitor

Definition
AI-generated

The GWAS Diversity Monitor is a public tracker that summarizes the ancestral composition of published genome-wide association studies by disease and field, quantifying how discovery remains skewed toward European-ancestry participants and highlighting progress over time.

Topics
Cohorts and databases
Related
Ancestry Participation Bias Polygenic Risk Score Portability

Why it matters in GWAS

It makes underrepresentation visible at scale, informs funding and cohort priorities, and contextualizes trans-ancestry replication and polygenic score limitations when base GWAS lack diversity.

Example usage

"We cited the GWAS Diversity Monitor to justify prioritizing replication in African ancestry samples for this trait category."

Ancestry Participation Bias Polygenic Risk Score Portability Trans-Ancestry GWAS
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Mills MC, Rahal C. (2020). The GWAS diversity monitor tracks diversity by disease in real time. Nat Genet.
  • Kuchenbaecker K, Navoly G. (2026). Ancestral diversity in complex disease genetics: from discovery to translation. Nat Rev Genet. https://doi.org/10.1038/s41576-025-00921-3
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