Trans-ancestry¶
Definition
AI-generated
Across ancestries; often denotes methods or meta-analyses explicitly pan-ancestry.
Topics
Why it matters in GWAS¶
Population structure, demographic history, and mating patterns affect allele frequencies, LD, relatedness, and cross-cohort portability—central to GWAS design and interpretation.
Example usage¶
"Trans-ancestry was modeled explicitly to reduce confounding and improve cross-cohort portability."
Related terms¶
References¶
- Hartl DL, Clark AG. (2007). Principles of Population Genetics. Sinauer Associates.
- Jobling MA, Hurles ME, Tyler-Smith C. (2013). Human Evolutionary Genetics. Garland Science.
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