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General Feature Format (GFF)

Definition
AI-generated

GFF is a tab-delimited format for describing genomic features and their coordinates, with a widely used modern variant called GFF3.

Topics
Bioinformatics Formats
URL
https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md
Related
Gene Transfer Format (GTF) Genome Annotation Genome Coordinate System

Why it matters in GWAS

GFF annotations are used when linking association signals to nearby genes and regulatory features, making coordinate consistency and feature semantics critical for robust interpretation.

Example usage

"At this locus, General Feature Format (GFF) annotations were used to prioritize plausible biological mechanisms."

Gene Transfer Format (GTF) Genome Annotation Genome Coordinate System
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • The Sequence Ontology. GFF3 Specification. https://github.com/The-Sequence-Ontology/Specifications/blob/master/gff3.md
← Geometric distribution ggplot2 →

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