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Gamete

Definition
AI-generated

A gamete is a haploid reproductive cell (sperm or egg) that carries one copy of each autosome and one sex chromosome, formed by meiosis from a diploid germline precursor.

Why it matters in GWAS

GWAS samples unrelated diploid individuals, but family-based designs and phasing exploit how alleles are transmitted through gametes; recombination in meiosis shapes the haplotypes that gametes carry.

Example usage

"Downstream interpretation uses Gamete to contextualize the main association signal."

References

  • Alberts B, et al. (2015). Molecular Biology of the Cell. 6th ed. Garland Science.

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