Skip to content

Anatomical Therapeutic Chemical Code (ATC)

Definition
AI-generated

The ATC classification assigns hierarchical codes to medicines by organ system (anatomical main group), therapeutic and pharmacological subgroup, and chemical substance.

Why it matters in GWAS

Pharmacogenomic and drug-response GWAS, PheWAS on medication use, and Mendelian randomization with drug proxies often aggregate exposures by ATC level; consistent coding matters for replication across countries and formularies.

Example usage

"We grouped statin prescriptions by ATC C10AA regardless of brand before testing genetic associations with adherence."

References

  • WHO Collaborating Centre for Drug Statistics Methodology. ATC/DDD Index. https://www.whocc.no/atc_ddd_index/

Last updated (UTC · Git history)