Anatomical Therapeutic Chemical Code (ATC)¶
Definition
AI-generated
The ATC classification assigns hierarchical codes to medicines by organ system (anatomical main group), therapeutic and pharmacological subgroup, and chemical substance.
Topics
Why it matters in GWAS¶
Pharmacogenomic and drug-response GWAS, PheWAS on medication use, and Mendelian randomization with drug proxies often aggregate exposures by ATC level; consistent coding matters for replication across countries and formularies.
Example usage¶
"We grouped statin prescriptions by ATC C10AA regardless of brand before testing genetic associations with adherence."
Related terms¶
References¶
- WHO Collaborating Centre for Drug Statistics Methodology. ATC/DDD Index. https://www.whocc.no/atc_ddd_index/
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