Acrocentric chromosome¶
Definition
AI-generated
Chromosome with centromere near one end and a prominent short arm (human acrocentrics carry rDNA repeats).
Topics
Why it matters in GWAS¶
GWAS hits are interpreted through gene structure, regulation, and variant consequence; molecular vocabulary connects association statistics to mechanism.
Example usage¶
"Cytogenetic review noted a Robertsonian translocation involving two acrocentric chromosome arms (13 and 14)."
Related terms¶
References¶
- Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.
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