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Acrocentric chromosome

Definition
AI-generated

Chromosome with centromere near one end and a prominent short arm (human acrocentrics carry rDNA repeats).

Why it matters in GWAS

GWAS hits are interpreted through gene structure, regulation, and variant consequence; molecular vocabulary connects association statistics to mechanism.

Example usage

"Cytogenetic review noted a Robertsonian translocation involving two acrocentric chromosome arms (13 and 14)."

References

  • Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.

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