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Quantile-quantile plot (QQ plot)

Definition
AI-generated

In GWAS, a QQ plot compares quantiles of observed association test statistics (or −log10 p) to their null expectation.

Topics
Visualization
Related
Matplotlib Genomic Inflation Factor Genome-Wide Association Study (GWAS)

Why it matters in GWAS

Systematic global inflation appears as a lifted curve above the diagonal and motivates checks for stratification, relatedness, or model misspecification; the intercept of LD score regression refines interpretation versus polygenicity.

Example usage

"The QQ plot showed inflation at the extreme tail only, consistent with polygenic signal rather than uncorrected structure."

Matplotlib Genomic Inflation Factor Genome-Wide Association Study (GWAS) Quality Control (QC)
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

← Python Quality Control (QC) →

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