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Polygenic Score Catalog

Definition
AI-generated

The Polygenic Score (PGS) Catalog is an open database of published polygenic scores and their performance metrics, harmonized metadata, and links to associated traits and publications.

Topics
Cohorts and databases
URL
https://www.pgscatalog.org/
Related
FAIR Principles Multi-Ancestry Polygenic Score Polygenic Risk Score (PRS)

Why it matters in GWAS

Researchers and clinicians can discover existing scores, ancestry contexts in which they were evaluated, and reporting standards—supporting equitable benchmarking as the field moves toward diverse validation.

Example usage

"Cross-cohort analyses modeled Polygenic Score Catalog to improve transferability and reduce population-structure confounding."

FAIR Principles Multi-Ancestry Polygenic Score Polygenic Risk Score (PRS) Polygenic Risk Score Portability PRS Base Cohort Trans-Ancestry GWAS
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Lambert SA, et al. (2021). The polygenic score catalog as an open database for reproducibility and systematic evaluation. Nat Genet.
  • Kachuri L, Chatterjee N, Hirbo J, et al. (2024). Principles and methods for transferring polygenic risk scores across global populations. Nat Rev Genet. https://doi.org/10.1038/s41576-023-00637-2
← Polygenic Risk Score Portability Polygyny →

Last updated (UTC · Git history)