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Mobile element insertion (MEI)

Definition
AI-generated

A mobile element insertion (MEI) is a transposable-element mediated insertion polymorphism.

Topics
Sequencing Data Analysis
Related
Structural Variant Transposable element

Why it matters in GWAS

MEIs contribute to rare structural variation; WGS enables tests that arrays largely miss.

Example usage

"MEI calls were intersected with gene bodies for exploratory burden analysis."

Structural Variant Transposable element
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Stewart C, et al. (2011). A comprehensive map of mobile element insertion polymorphisms in humans. PLoS Genet.
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