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Long interspersed nuclear element (LINE)

Definition
AI-generated

Autonomous retrotransposon class abundant in mammalian genomes; mobilizes via reverse transcription.

Why it matters in GWAS

GWAS hits are interpreted through gene structure, regulation, and variant consequence; molecular vocabulary connects association statistics to mechanism.

Example usage

"A replication step checks whether Long interspersed nuclear element (LINE) assumptions remain stable across cohorts."

References

  • Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.

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