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Heterochromatin

Definition
AI-generated

Tightly packed chromatin generally associated with lower gene density or silencing—contrasts with euchromatin.

Why it matters in GWAS

GWAS hits are interpreted through gene structure, regulation, and variant consequence; molecular vocabulary connects association statistics to mechanism.

Example usage

"Functional assays used Heterochromatin context to connect noncoding variants with regulatory effects."

References

  • Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.

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