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Cytosine (C)

Definition
AI-generated

Pyrimidine base pairing with guanine (DNA methylation commonly occurs on C in CpG).

Why it matters in GWAS

GWAS hits are interpreted through gene structure, regulation, and variant consequence; molecular vocabulary connects association statistics to mechanism.

Example usage

"A cytosine-to-thymine transition at this site was consistent with known deamination patterns in ancient DNA."

References

  • Griffiths AJF, et al. (2015). An Introduction to Genetic Analysis. W. H. Freeman.

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