Skip to content

Callability

Definition
AI-generated

Callability describes whether a locus or sample meets preset evidence thresholds for reliable genotype inference—typically combining depth, mapping and base quality, and sometimes allelic balance or strand balance.

Topics
Sequencing Data Analysis
Related
Callable genome Genotype quality (GQ) No-call

Why it matters in GWAS

Differences in callability across ancestries or batches can create artifactual frequency shifts; explicit callability models underpin GVCF and joint genotyping workflows.

Example usage

"Per-site callability was exported alongside the VCF for downstream masking."

Callable genome Genotype quality (GQ) No-call
Related-term network

Click any node to open that term page.

Node order. The current term is first. Next come every page linked from Related terms, in the same top-to-bottom order as that list. Then new terms appear in two-hop layers: for each of those direct neighbors (in that same order), their related terms are appended if not already listed. A third pass does the same for two-hop nodes. The walk stops when a fixed maximum number of nodes is reached.

References

  • Poplin R, et al. (2017). Scaling accurate genetic variant discovery to tens of thousands of samples. bioRxiv (GATK).
← Call Rate Callable genome →

Last updated (UTC · Git history)